BioMed Alliance Taskforce on Academic Clinical Trials

A main pillar under the Reducing Bureaucracy in Clinical Trials Coalition, this BioMed Alliance taskforce develops and supports a range of initiatives in support of academic clinical trials.

Good Clinical Trials Collaborative

Funded by Wellcome, the Gates Foundation and the African Academy of Sciences, the GCTC has set out to review the principles of randomised clinical trials for all types of healthcare interventions.

International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH)

Global consortium of regulatory authorities and pharmaceutical industry aiming to harmonize the development and registration of safe, effective and high-quality medicines. Currently the revision is under way of the ICH E6 guideline “Good Clinical Practice (GCP)”.

EORTC Manifesto on Treatment Optimisation

Launched at a joint event with the BioMed Alliance and the European Parliament’s STOA Panel in January 2019, this manifesto calls for establishing Treatment Optimization as part of personalized medicine development. EORTC and its fellow signatories call for turning the regulatory approval-oriented clinical research landscape into a truly patient-centered system combining drug development with comparative effectiveness studies and long-term safety monitoring.


TranspariMED is a campaign advocating for more clinical trial transparency and better outcome reporting.


The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) is an American membership-based scientific organization that designs and conducts cancer research involving adults who have or are at risk of developing cancer.


den Heijer, JM, Heuberger, JAAC, Hijma, H, et al. Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines. Br J Clin Pharmacol. 2021; 87( 12): 4552– 4559.

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Gribben J, et al. Reducing Bureaucracy in Clinical Research: A Call for Action, HemaSphere, March 2020 doi:10.1097/HS9.0000000000000352

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Perez-Gracia JL, Awada A, Calvo E, et al. ESMO Clinical Research Observatory (ECRO): improving the efficiency of clinical research through rationalisation of bureaucracy, ESMO Open, May 2020 doi: 10.1136/esmoopen-2019-000662

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